Psychiatric and social outcome following liver transplantation for alcoholic liver disease: A controlled study

Psychiatric outcome, quality of life, and alcohol consumption were compared between patients transplanted for alcoholic liver disease and those transplanted for other chronic liver diseases. Instruments used included the Clinical Interview Schedule, the 28-item General Health Questionnaire, the Hosp...

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Bibliographic Details
Published in:Journal of psychosomatic research 1999-04, Vol.46 (4), p.359-368
Main Authors: Gledhill, Julia, Burroughs, Andrew, Rolles, Keith, Davidson, Brian, Blizard, Bob, Lloyd, Geoffrey
Format: Article
Language:English
Subjects:
Adult
Aged
Alcohol Drinking - epidemiology
Alcoholic
Alcoholism and acute alcohol poisoning
Biological and medical sciences
Case-Control Studies
England
Female
Humans
Liver Cirrhosis, Alcoholic - economics
Liver Cirrhosis, Alcoholic - psychology
Liver Cirrhosis, Alcoholic - therapy
Liver transplantation
Liver Transplantation - adverse effects
Liver Transplantation - mortality
Liver Transplantation - psychology
Male
Medical sciences
Mental Disorders - complications
Middle Aged
Outcome Assessment (Health Care) - statistics & numerical data
Patient Compliance
Postoperative Complications - physiopathology
Postoperative Complications - psychology
Psychosocial
Recidivism
Social Adjustment
Survival Rate
Toxicology
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Summary:Psychiatric outcome, quality of life, and alcohol consumption were compared between patients transplanted for alcoholic liver disease and those transplanted for other chronic liver diseases. Instruments used included the Clinical Interview Schedule, the 28-item General Health Questionnaire, the Hospital Anxiety and Depression Scale, and the Nottingham Health Profile. There was no difference between the two groups with regard to median scores or “caseness” on these instruments, except for physical mobility on the Nottingham Health Profile, where the alcoholic group was more likely to experience difficulties ( p=0.03). The majority of those transplanted for alcoholic liver disease remained abstinent, although 7 of the 31 in the alcoholic group (23%) were drinking above recommended safe limits. Psychosocial outcome is similar for individuals transplanted for alcoholic liver disease and those transplanted for other chronic liver diseases. Patients should not be excluded from transplantation on grounds of their drinking history.
ISSN:0022-3999
1879-1360
DOI:10.1016/S0022-3999(98)00123-8