Are There Changes in Gastric Emptying during the Menstrual Cycle?

Background: The questions of whether gastric emptying of solids and liquids differs in men and women and whether emptying is influenced by the action of sex hormones on gastric smooth muscle remain unresolved. Methods: We analysed the gastric emptying of digestible solids (GES), liquids (GEL), and r...

Full description

Saved in:
Bibliographic Details
Published in:Scandinavian journal of gastroenterology 1999, Vol.34 (8), p.772-776
Main Author: A. M. Caballero-Plasencia, M. Valenzuela-Barranco, J. L. Martín-Ruiz, J. M. Herrerías-Gutiérrez, J. M. Esteban-Carretero
Format: Article
Language:English
Subjects:
Adult
Barium Sulfate
Biological and medical sciences
Estradiol - blood
Female
Follicular Phase - physiology
Food, Formulated
Fundamental and applied biological sciences. Psychology
Gastric Emptying - physiology
Humans
Luteal Phase - physiology
Male
Menstrual Cycle - physiology
Progesterone - blood
Radioactive Tracers
Radiography
Sex Factors
Statistics, Nonparametric
Stomach
Vertebrates: digestive system
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: The questions of whether gastric emptying of solids and liquids differs in men and women and whether emptying is influenced by the action of sex hormones on gastric smooth muscle remain unresolved. Methods: We analysed the gastric emptying of digestible solids (GES), liquids (GEL), and radiopaque indigestible solids (GER) in three groups of healthy volunteers: 50 women in the follicular phase of the menstrual cycle, 50 women in the luteal phase, and 100 men. [99mTc]-labelled diethylenetriamine pentaacetic acid (DTPA) was used as the radioactive marker for digestible solids, and [111In]DTPA was used as the marker for liquids, to time gastric motility after a solid and a liquid meal. GER was evaluated on a different day in abdominal roentgenograms. Results: GES and GEL were slower in women than in men (P < 0.05), but GER was similar in the two sexes. However, there were no significant differences in GES, GEL, or GER between women in the follicular and those in the luteal phase, between plasma concentrations of oestradiol and progesterone and the variables used to characterize gastric emptying. Conclusions: Evidence of postprandial 'physiologic gastroparesis' was found in women, although no differences were found between men and women in gastric motility during fasting. The rate of emptying was not related to changes in plasma concentrations of sex hormones during the menstrual cycle.
ISSN:0036-5521
1502-7708
DOI:10.1080/003655299750025697