Population Data on the Thirteen CODIS Core Short Tandem Repeat Loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians

Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11, were determined in African American, United States Caucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations....

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Bibliographic Details
Published in:Journal of forensic sciences 1999-11, Vol.44 (6), p.1277-1286
Main Authors: Budowle, B, Moretti, TR, Baumstark, AL, Defenbaugh, DA, Keys, KM
Format: Article
Language:English
Subjects:
Adult
Alleles
Bahamas - epidemiology
Black or African American
Black people
Black People - genetics
Databases, Factual
Deoxyribonucleic acid
DNA
DNA Fingerprinting
Ethnicity - genetics
Forensic Medicine - methods
Forensic sciences
Genetics
Genetics, Population
Hispanic Americans
Hispanic or Latino - genetics
Humans
Jamaica - epidemiology
Population
Tandem Repeat Sequences - genetics
Trinidad and Tobago - epidemiology
United States - epidemiology
White people
White People - genetics
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Summary:Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, and D21S11, were determined in African American, United States Caucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Based on the exact test, the loci that departed significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p = 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Caucasians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni correction for the number of loci analyzed (i.e., 13 loci per database), these observations are not likely to be significant. There is little evidence for association of alleles between the loci in these databases. The allelic frequency data are similar to other comparable data within the same major population group.
ISSN:0022-1198
1556-4029
DOI:10.1520/JFS14601J