Long-term Vestibulo-ocular Reflex Changes in Patients with Vestibular Ablation

Long-term changes in the parameters of the vestibulo-ocular reflex (VOR) were evaluated using recently developed multilevel statistical modelling techniques in a group of patients who had undergone ablative inner ear procedures. Data from 84 patients were available for study. The most dramatic recov...

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Bibliographic Details
Published in:Acta oto-laryngologica 2000, Vol.120 (2), p.187-191
Main Authors: Jenkins, H A, Cohen, H S, Kimball, K T
Format: Article
Language:English
Subjects:
Female
Follow-Up Studies
Functional Laterality - physiology
Humans
Male
Middle Aged
Models, Statistical
Neuroma, Acoustic - physiopathology
Neuroma, Acoustic - surgery
Postoperative Complications - physiopathology
Predictive Value of Tests
Reflex, Vestibulo-Ocular - physiology
Vestibular Function Tests
Vestibular Nerve - physiopathology
Vestibular Nerve - surgery
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Summary:Long-term changes in the parameters of the vestibulo-ocular reflex (VOR) were evaluated using recently developed multilevel statistical modelling techniques in a group of patients who had undergone ablative inner ear procedures. Data from 84 patients were available for study. The most dramatic recovery in the VOR occurred during the first 60 postoperative days, however, slow changes continued, levelling off at about 120 days. While frequency was a highly significant predictor of outcomes in all parameters, age showed significant predictive value only to phase measures (p=0.006) and gender had no effect. Sum gain at the lowest frequency tested remained below the 5th percentile and at the higher frequencies remained below the 50th percentile for normal subjects. Phase decreased exponentially, but remained above the 95th percentile for normal subjects, except at the highest frequency where it remained above the 50th percentile. DC bias decreased exponentially, dropping to the 50th percentile by day 146. Asymmetry stayed between the 50th and 95th percentile, except at the highest frequency, where it was at the 50th percentile by day 125.
ISSN:0001-6489
1651-2251
DOI:10.1080/000164800750000883