Significance of platelet aggregability immediately after blood sampling and effect of cigarette smoking

A novel type platelet aggregometer, a WBA Analyzer, has enabled us to obtain the platelet aggregability data immediately after blood sampling, which is considered to closely reflect in vivo platelet function. Using this analyzer, we measured the platelet aggregatory threshold index (PATI) 5 min afte...

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Bibliographic Details
Published in:Platelets (Edinburgh) 2001, Vol.12 (7), p.415-418
Main Authors: Inoue, Teruo, Hayashi, Masatoshi, Uchida, Toshihiko, Takayanagi, Kan, Hayashi, Terumi, Morooka, Shigenori
Format: Article
Language:English
Subjects:
Adult
Blood Specimen Collection - standards
Humans
Male
Nephelometry and Turbidimetry - instrumentation
Platelet Aggregation
Platelet Function Tests - instrumentation
Platelet Function Tests - methods
Platelet Function Tests - standards
Scattering, Radiation
Smoking - adverse effects
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Summary:A novel type platelet aggregometer, a WBA Analyzer, has enabled us to obtain the platelet aggregability data immediately after blood sampling, which is considered to closely reflect in vivo platelet function. Using this analyzer, we measured the platelet aggregatory threshold index (PATI) 5 min after blood sampling and compared it with that 60 min after blood sampling in 20 healthy male volunteers (10 smokers and 10 non-smokers). In the non-smokers, PATI was 10.3 - 2.3 w M 5 min after blood sampling, and it decreased to 4.7 - 1.5 ( P
ISSN:0953-7104
1369-1635
DOI:10.1080/09537100120071068