Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000

• Published in: Antimicrobial Agents and Chemotherapy 2002-01, Vol.46 (1), p.119-124
• Main Authors: DAVIES, Todd A, EVANGELISTA, Alan, PFLEGER, Sharon, BUSH, Karen, SAHM, Daniel F, GOLDSCHMIDT, Raul
• Format: Article
• Language: English
• Subjects: Anti-Infective Agents; Anti-Infective Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacteriology; Biological and medical sciences; DNA Topoisomerases, Type II; DNA Topoisomerases, Type II - genetics; Fundamental and applied biological sciences. Psychology; Gene Frequency; Genetics; Humans; Levofloxacin; Medical sciences; Metabolism. Enzymes; Microbial Sensitivity Tests; Microbiology; Ofloxacin; Ofloxacin - pharmacology; Pharmacology. Drug treatments; Point Mutation; Streptococcus pneumoniae; Streptococcus pneumoniae - drug effects; Streptococcus pneumoniae - enzymology; Streptococcus pneumoniae - genetics; Susceptibility; United States
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.46.1.119-124.2002

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