Adhesion Induced by Mobile Binders: Dynamics

We consider a vesicle bilayer loaded with molecules that can bind (upon contact) with a solid surface, following the classical model of Bell, Dembo, and Bongrand. We are interested in situations where the contact area varies with time: we assume that binders can then migrate via diffusion. The resul...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2002-06, Vol.99 (12), p.7854-7859
Main Authors: Brochard-Wyart, F., de Gennes, P. G.
Format: Article
Language:English
Subjects:
Adhesion
Adhesives
Cell Adhesion - physiology
Diffusion length
Flow velocity
Hydrodynamics
Ideal gas
Interfacial tension
Ligands
Models, Biological
Molecules
Osmosis
Physical Sciences
Surface areas
Viscosity
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Summary:We consider a vesicle bilayer loaded with molecules that can bind (upon contact) with a solid surface, following the classical model of Bell, Dembo, and Bongrand. We are interested in situations where the contact area varies with time: we assume that binders can then migrate via diffusion. The resulting dissipation and lag create a retarded force on the contact line, which could be significant in squeezing or rolling experiments. However, there are two cases where we expect the lag force to be ineffective: (i) separation by shrinking of an adhesive patch (where the Evans "tear out" process turns out to be less costly) and (ii) spontaneous growth of a patch from a point contact. In this last case, the lag force is weak, and we give detailed predictions for the growth laws.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.112221299