Attention deficit/hyperactivity disorder and methylphenidate: A review of height/weight, cardiovascular, and somatic complaint side effects

Three classes (height/weight, cardiovascular, and somatic complaints) of treatment emergent symptoms (side effects) associated with methylphenidate (MPH) therapy for children with attention deficit/hyperactivity disorder (ADHD) are reviewed. The more easily quantifiable side effects (e.g., blood pre...

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Bibliographic Details
Published in:Clinical Psychology Review 2002-11, Vol.22 (8), p.1107-1131
Main Authors: Rapport, Mark D, Moffitt, Catherine
Format: Article
Language:English
Subjects:
Attention Deficit Disorder with Hyperactivity - drug therapy
Blood Pressure - drug effects
Body Height - drug effects
Body Weight - drug effects
Central Nervous System Stimulants - adverse effects
Central Nervous System Stimulants - therapeutic use
Child
Clinical Trials as Topic
Heart Rate - drug effects
Humans
Methylphenidate - adverse effects
Methylphenidate - therapeutic use
Risk Factors
Treatment Outcome
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Summary:Three classes (height/weight, cardiovascular, and somatic complaints) of treatment emergent symptoms (side effects) associated with methylphenidate (MPH) therapy for children with attention deficit/hyperactivity disorder (ADHD) are reviewed. The more easily quantifiable side effects (e.g., blood pressure [BP], heart rate [HR], height/weight) are mostly transient, dose-dependent, easily rectified with dosage adjustments, and considered minor from a clinical perspective considering the breadth and level of improvement in behavior and cognitive functioning observed in most children. Previously reported somatic complaints associated with psychostimulant therapy may reflect symptoms occurring prior to initiation of treatment and require additional study.
ISSN:0272-7358
1873-7811
DOI:10.1016/S0272-7358(02)00129-0