Efficient characterization of regional mesenteric blood flow by use of laser speckle imaging

We present a noninvasive full-field method--laser speckle imaging (LSI)--for measuring the regional mesenteric blood flow without scanning. A system of LSI was designed and validated in a model experiment. Dynamics of regional blood flow in the rat mesentery under the influence of noradrenaline were...

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Bibliographic Details
Published in:Applied optics (2004) 2003-10, Vol.42 (28), p.5759
Main Authors: Cheng, Haiying, Luo, Qingming, Wang, Zheng, Gong, Hui, Chen, Shangbin, Liang, Wenxi, Zeng, Shaoqun
Format: Article
Language:English
Subjects:
Animals
Diagnostic Imaging
Lasers
Male
Models, Theoretical
Rats
Rats, Wistar
Splanchnic Circulation
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Summary:We present a noninvasive full-field method--laser speckle imaging (LSI)--for measuring the regional mesenteric blood flow without scanning. A system of LSI was designed and validated in a model experiment. Dynamics of regional blood flow in the rat mesentery under the influence of noradrenaline were monitored by this method. Spatial and temporal characteristics of the mesenteric blood-flow response were achieved with high resolution. These suggested that LSI might provide a new approach to microcirculation studies.
ISSN:1559-128X
DOI:10.1364/ao.42.005759