ANDROPAUSE: ENDOCRINOLOGY, ERECTILE DYSFUNCTION, AND PROSTATE PATHOPHYSIOLOGY

This review summarizes major biological aspects of andrology of andropause, deficiency in androgens/growth hormones, and molecular parameters; erectile dysfunction (ED), the use of malleable, mechanical, inflatable devices as well as the application of Viagra (Sildenafil), alprotadil (Caverject), Yo...

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Bibliographic Details
Published in:Archives of andrology 2004-03, Vol.50 (2), p.45-68
Main Authors: HAFEZ, B., HAFEZ, E. S. E.
Format: Article
Language:English
Subjects:
Androgens - physiology
andropause
Animals
Biological and medical sciences
Climacteric - physiology
endocrinology
Erectile Dysfunction - drug therapy
Erectile Dysfunction - pathology
Erectile Dysfunction - physiopathology
Fundamental and applied biological sciences. Psychology
Gynecology. Andrology. Obstetrics
Humans
Male
Male genital diseases
Mammalian male genital system
Medical sciences
osteoporosis
pathophysiology
prostate
Prostatic Neoplasms - drug therapy
Prostatic Neoplasms - pathology
Prostatic Neoplasms - physiopathology
Vertebrates: reproduction
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Summary:This review summarizes major biological aspects of andrology of andropause, deficiency in androgens/growth hormones, and molecular parameters; erectile dysfunction (ED), the use of malleable, mechanical, inflatable devices as well as the application of Viagra (Sildenafil), alprotadil (Caverject), Yohimbine, and other drugs not yet approved by FDA, such as Papaverine, phentolamine (Vasomax), and apormorphine (Uprima); osteopenia/osteoporosis: testosterone/osteoporesis; supplementation during andropause: administration of andiogens, possible risk factors of androgens, calcium supplement and muscle mass; prostate pathophysiology: consequences of prostatectomy, prostate cancer, benign prostatic hyperplasia (BPH), hormone-dependent cancers; bladder and urethral dysfunction: neurological parameter, urodynamics technology; models on aging in male animals: comparative physiology of prostate of laboratory animals/farm animals; future research: functional anatomy of male reproductive organs, pharmacokinetics of osteoporosis, endocrinology/neuroendocrinology/chromosome anomalies supplementation during andropause, experimental animal models and future multicenter multidisciplinary research.
ISSN:0148-5016
1521-0375
DOI:10.1080/01485010490274131