Synthesis and Molluscicidal Activity of 5-oxo-5,6,7,8-Tetrahydro-4H-Chromene Derivatives

Furfurylidenemalononitriles and thienylidenemalononitriles were treated with 1,3‐cyclohexanediones to afford 2‐amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile derivatives. The molluscicidal activity of these compounds was investigated.

Saved in:
Bibliographic Details
Published in:Archiv der Pharmazie (Weinheim) 2004-09, Vol.337 (9), p.482-485
Main Authors: Abdelrazek, Fathy M., Metz, Peter, Farrag, Ebtehal K.
Format: Article
Language:English
Subjects:
1,3‐cyclo‐ hexanediones
2-Amino-4-hetaryl-5-oxo-5
2‐Amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitriles
3-cyclo- hexanediones
8-tetrahydro-4H-chromene-3-carbonitriles
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiparasitic agents
Benzopyrans - chemical synthesis
Benzopyrans - chemistry
Benzopyrans - pharmacology
Biological and medical sciences
Biomphalaria - drug effects
Furfurylidenemalononitriles
Medical sciences
Molecular Structure
Molluscacides - chemical synthesis
Molluscacides - chemistry
Molluscacides - pharmacology
Pharmacology. Drug treatments
Structure-Activity Relationship
Thienylidenemalononitriles
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Furfurylidenemalononitriles and thienylidenemalononitriles were treated with 1,3‐cyclohexanediones to afford 2‐amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile derivatives. The molluscicidal activity of these compounds was investigated.
ISSN:0365-6233
1521-4184
DOI:10.1002/ardp.200400881