Near‐real‐time radiotherapy dosimetry using optically stimulated luminescence of Al2O3:C: Mathematical models and preliminary results

In this paper we report investigations aimed toward applying optically stimulated luminescence (OSL) of Al2O3:C for near‐real‐time medical dosimetry, especially in radiotherapy. The classical mathematical model normally used for the description of OSL phenomena was expanded to predict the behavior o...

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Bibliographic Details
Published in:Medical physics (Lancaster) 2005-04, Vol.32 (4), p.1094-1102
Main Authors: Gaza, R., McKeever, S. W. S., Akselrod, M. S.
Format: Article
Language:English
Subjects:
Algorithms
aluminium compounds
Aluminum Oxide - chemistry
carbon
dosimetry
Electromagnetic radiation detectors
Electrons
Film Dosimetry
Laser beam effects
Lasers
Luminescence
Luminescent Measurements
Models, Statistical
Models, Theoretical
optical fibres
Optical sensors
Optically stimulated luminescence
Ozone
photoluminescence
Quality assurance in radiotherapy
Radiation detectors
Radiation Dosage
radiation therapy
Radiometry - methods
Radiotherapy Dosage
Solid‐state detectors
Strontium Radioisotopes
Thermoluminescent Dosimetry - methods
Time Factors
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Summary:In this paper we report investigations aimed toward applying optically stimulated luminescence (OSL) of Al2O3:C for near‐real‐time medical dosimetry, especially in radiotherapy. The classical mathematical model normally used for the description of OSL phenomena was expanded to predict the behavior of the luminescence signal in the case when the OSL sample is simultaneously irradiated and optically stimulated. The predictions obtained were used to develop different measurement approaches and correction algorithms for the luminescence signals, thus enabling dose estimation from OSL during rather then after the irradiation procedure. Radiation probes with diameters of less than 1 mm, suitable for the envisioned in‐vivo measurements were constructed by attaching small Al2O3:C crystals to optical fiber cables. The OSL fiber probes and a purpose‐built, portable OSL stimulation and readout system were used to measure doses at speeds up to 1 data point every 3s, under irradiation at dose rates of the same order of magnitude as those found in conventional radiotherapy techniques. The corrected OSL signal was found to be proportional to the absorbed dose, and accurately followed sudden transitions in the irradiation dose rate.
ISSN:0094-2405
2473-4209
DOI:10.1118/1.1884365