Anthracycline-induced heart failure aggravated by pregnancy. Survival after cardiac assistance with artificial heart device and heart transplantation

We report a case of a young woman suffering from a steady anthracycline-induced myocardiopathy with a decreased left ventricular function on echocardiography. A pregnancy was initiated, without worsening of the cardiopathy until 34 weeks. Nine days after delivery, an acute heart failure was observed...

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Bibliographic Details
Published in:Annales françaises d'anesthésie et de réanimation 2005-07, Vol.24 (7), p.826
Main Authors: Adel, M, Dubé, L, Treilhaud, M, Burban, M, Despins, P, Blanloeil, Y
Format: Article
Language:fre
Subjects:
Adult
Anthracyclines - adverse effects
Echocardiography
Female
Heart Failure - chemically induced
Heart Failure - complications
Heart Transplantation
Heart-Assist Devices
Humans
Pregnancy
Pregnancy Complications, Cardiovascular - surgery
Ventricular Dysfunction, Left - chemically induced
Ventricular Dysfunction, Left - complications
Ventricular Dysfunction, Left - surgery
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Summary:We report a case of a young woman suffering from a steady anthracycline-induced myocardiopathy with a decreased left ventricular function on echocardiography. A pregnancy was initiated, without worsening of the cardiopathy until 34 weeks. Nine days after delivery, an acute heart failure was observed leading to heart transplantation after cardiac assistance with heart cardiac device. As pregnancy is an extended stress test for a chronic failing heart, a multidisciplinary decision of pregnancy initiation and follow up should be preferred in pre and postpartum period, when such a cardiopathy exists.
ISSN:0750-7658
DOI:10.1016/j.annfar.2005.04.026