A particle swarm optimization algorithm for beam angle selection in intensity-modulated radiotherapy planning

• Published in: Physics in medicine & biology 2005-08, Vol.50 (15), p.3491-3514
• Main Authors: Li, Yongjie, Yao, Dezhong, Yao, Jonathan, Chen, Wufan
• Format: Article
• Language: English
• Subjects: Algorithms; Body Burden; Computer Simulation; Dose-Response Relationship, Radiation; Humans; Male; Models, Biological; Prostatic Neoplasms - physiopathology; Prostatic Neoplasms - radiotherapy; Radiometry - methods; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Radiotherapy, Conformal - methods; Relative Biological Effectiveness; Treatment Outcome
• ISSN: 0031-9155; 1361-6560
• DOI: 10.1088/0031-9155/50/15/002

Automatic beam angle selection is an important but challenging problem for intensity-modulated radiation therapy (IMRT) planning. Though many efforts have been made, it is still not very satisfactory in clinical IMRT practice because of overextensive computation of the inverse problem. In this paper, a new technique named BASPSO (Beam Angle Selection with a Particle Swarm Optimization algorithm) is presented to improve the efficiency of the beam angle optimization problem. Originally developed as a tool for simulating social behaviour, the particle swarm optimization (PSO) algorithm is a relatively new population-based evolutionary optimization technique first introduced by Kennedy and Eberhart in 1995. In the proposed BASPSO, the beam angles are optimized using PSO by treating each beam configuration as a particle (individual), and the beam intensity maps for each beam configuration are optimized using the conjugate gradient (CG) algorithm. These two optimization processes are implemented iteratively. The performance of each individual is evaluated by a fitness value calculated with a physical objective function. A population of these individuals is evolved by cooperation and competition among the individuals themselves through generations. The optimization results of a simulated case with known optimal beam angles and two clinical cases (a prostate case and a head-and-neck case) show that PSO is valid and efficient and can speed up the beam angle optimization process. Furthermore, the performance comparisons based on the preliminary results indicate that, as a whole, the PSO-based algorithm seems to outperform, or at least compete with, the GA-based algorithm in computation time and robustness. In conclusion, the reported work suggested that the introduced PSO algorithm could act as a new promising solution to the beam angle optimization problem and potentially other optimization problems in IMRT, though further studies need to be investigated.