KINETIC MODEL OF OXIDATION CATALYZED BY XANTHINE OXIDASE-THE FINAL ENZYME IN DEGRADATION OF PURINE NUCLEOSIDES AND NUCLEOTIDES

A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an equation which is a rational function of degree...

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Published in:Nucleosides, nucleotides & nucleic acids nucleotides & nucleic acids, 2005-01, Vol.24 (5-7), p.465-469
Main Authors: Banach, Kinga, Bojarska, Elżbieta, Kazimierczuk, Zygmunt, Magnowska, Lucyna, Bzowska, Agnieszka
Format: Article
Language:English
Subjects:
Adenine - analogs & derivatives
Adenine - chemistry
Biological Oxidation
Chemical Phenomena
Chemistry
Enzyme Kinetics
Hydrogen-Ion Concentration
Inhibitory Concentration 50
Kinetics
Models, Theoretical
Non-Michaelis-Menten Kinetics
Oxygen - chemistry
Purine Degradation
Purine Nucleosides - chemistry
Regression Analysis
Xanthine - chemistry
Xanthine Oxidase
Xanthine Oxidase - chemistry
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creator Banach, Kinga
Bojarska, Elżbieta
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description A new kinetic model is presented for analysis of experimental data of oxidation process catalyzed by milk xanthine oxidase. The kinetics for two substrates, xanthine and its analog 2-chloroadenine, in a broad pH range (5.8-9.0) are best described by an equation which is a rational function of degree 2:3 and 2:2, respectively.
doi_str_mv 10.1081/NCN-200060006
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source Taylor and Francis Science and Technology Collection
subjects Adenine - analogs & derivatives
Adenine - chemistry
Biological Oxidation
Chemical Phenomena
Chemistry
Enzyme Kinetics
Hydrogen-Ion Concentration
Inhibitory Concentration 50
Kinetics
Models, Theoretical
Non-Michaelis-Menten Kinetics
Oxygen - chemistry
Purine Degradation
Purine Nucleosides - chemistry
Regression Analysis
Xanthine - chemistry
Xanthine Oxidase
Xanthine Oxidase - chemistry
title KINETIC MODEL OF OXIDATION CATALYZED BY XANTHINE OXIDASE-THE FINAL ENZYME IN DEGRADATION OF PURINE NUCLEOSIDES AND NUCLEOTIDES
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