Lymphadenopathy and constitutional symptoms. Progress of a low-grade follicular lymphoma?

Atypical presentation of Churg-Strauss syndrome includes lymph-node and parenchymatous organ involvement which mimics the clinical presentation of lymphoproliferative disorders.A 54-year old man with a history of a low-grade follicular lymphoma presented with rapidly growing abdominal lymph-nodes an...

Full description

Saved in:
Bibliographic Details
Published in:Der Internist (Berlin) 2006-05, Vol.47 (5), p.528
Main Authors: Stemmler, H J, Hoelzl, M, Moosmann, N, Becker, C, Lennertz, A, Babaryka, G
Format: Article
Language:ger
Subjects:
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biopsy
Churg-Strauss Syndrome - diagnosis
Combined Modality Therapy
Diagnosis, Differential
Disease Progression
Humans
Lymphatic Diseases - etiology
Lymphoma, Follicular - diagnosis
Lymphoma, Follicular - drug therapy
Lymphoma, Follicular - radiotherapy
Male
Middle Aged
Radiotherapy, Adjuvant
Tomography, X-Ray Computed
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Atypical presentation of Churg-Strauss syndrome includes lymph-node and parenchymatous organ involvement which mimics the clinical presentation of lymphoproliferative disorders.A 54-year old man with a history of a low-grade follicular lymphoma presented with rapidly growing abdominal lymph-nodes and hepatic, renal and pulmonary infiltrations. CT guided biopsies to verify either lymphoma or infections showed eosinophilic, necrotizing, granulomatous vasculitis leading to the diagnosis of atypical Churg-Strauss syndrome. Within a few days of cyclophosphamide and prednisone treatment the clinical presentation improved and imaging studies detected regression of all manifestations during follow-up.
ISSN:0020-9554
DOI:10.1007/s00108-005-1563-x