Oxytocin and maternal stress during the post-partum period

• Published in: Annales d'endocrinologie 2006-06, Vol.67 (3), p.214
• Main Authors: Boutet, C, Vercueil, L, Schelstraete, C, Buffin, A, Legros, J J
• Format: Article
• Language: fre
• Subjects: Adult; Depression, Postpartum - etiology; Depression, Postpartum - physiopathology; Depression, Postpartum - psychology; Female; Hormones - physiology; Humans; Oxytocin - physiology; Postpartum Period - physiology; Pregnancy; Receptors, Oxytocin - physiology; Stress, Physiological - physiopathology
• ISSN: 0003-4266

Oxytocin is required for lactation by promoting milk expulsion. Oxytocin has also been reported to exert a positive role in social attachment. The postpartum period has been shown to be crucial for maternal behavior initiation, and required self-trust reinforcement. However, this period is also remarkable for the high risk exposure of either psychic or physical stress. A negative impact on young mother is suspected, both in the short, medium or long term, which can even be deleterious for child-mother relationships. During lactation in female rats and sheep, oxytocin production has been proved to decrease stress-induced hormonal changes and later consequences. In human beings, only the first hour after breast-feeding seems to protect against physical or psychic stress. Oxytocin improves the stress-induced response by reducing the ACTH and cortisol secretion thus representing a potential therapeutic pathway in post-partum pathologies such as depression. Thus, this review of recent literature about oxytocin and stress during post-partum period, leads to the assumption that oxytocin, at the moment of installation of breastfeeding, acts not only on the physiological condition, but also on the psychic condition of the mother.