Phylogeny of Viroids, Viroidlike Satellite RNAs, and the Viroidlike Domain of Hepatitis δ Virus RNA

We report a phylogenetic study of viroids, some plant satellite RNAs, and the viroidlike domain of human hepatitis δ virus RNA. Our results support a monophyletic origin of these RNAs and are consistent with the hypothesis that they may be "living fossils" of a precellular RNA world. Moreo...

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1991-07, Vol.88 (13), p.5631-5634
Main Authors: Elena, Santiago F., Dopazo, Joaquin, Flores, Ricardo, Diener, Theodor O., Moya, Andres
Format: Article
Language:English
Subjects:
Artificial satellites
Biological and medical sciences
Evolution
Fundamental and applied biological sciences. Psychology
Hepatitis
Hepatitis delta virus
Hepatitis Delta Virus - genetics
Microbiology
Models, Biological
Nucleic acids
Phylogenetics
Phylogeny
RNA
RNA - genetics
RNA, Satellite
RNA, Viral - genetics
Satellite RNA
Systematics
Viroids
Viroids - genetics
Virology
Viruses
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Summary:We report a phylogenetic study of viroids, some plant satellite RNAs, and the viroidlike domain of human hepatitis δ virus RNA. Our results support a monophyletic origin of these RNAs and are consistent with the hypothesis that they may be "living fossils" of a precellular RNA world. Moreover, the viroidlike domain of human hepatitis δ virus RNA appears closely related to the viroidlike satellite RNAs of plants, with which it shares some structural and functional properties. On the basis of our phylogenetic analysis, we propose a taxonomic classification of these RNAs.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.88.13.5631