Clear cell tumor of the lung. A case report with review of the literature

Clear-cell tumor of the lung is a rare entity of unknown etiology and histogenesis. This neoplasm typically presents as an asymptomatic, peripheral, sharply rounded mass in the lung, and histologically composed of large cells with a clear cytoplasm rich in glycogen, blended with an abundant network...

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Bibliographic Details
Published in:Revue de pneumologie clinique 2006-12, Vol.62 (6 Pt 1), p.395
Main Authors: Ayadi-Kaddour, A, Ben Slama, S, Braham, E, Abid, L, Djilani, H, Ismail, O, Kilani, T, El Mezni, F
Format: Article
Language:fre
Subjects:
Adenocarcinoma, Clear Cell - chemistry
Adenocarcinoma, Clear Cell - diagnosis
Adenocarcinoma, Clear Cell - diagnostic imaging
Adenocarcinoma, Clear Cell - pathology
Adenocarcinoma, Clear Cell - surgery
Adult
Antigens, Neoplasm
Biomarkers, Tumor - analysis
Cytoplasm - chemistry
Diagnosis, Differential
Female
Glycogen - analysis
Humans
Immunohistochemistry
Lung Neoplasms - chemistry
Lung Neoplasms - diagnosis
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Melanoma-Specific Antigens
Neoplasm Proteins - analysis
Pneumonectomy
Radiography
Treatment Outcome
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Description
Summary:Clear-cell tumor of the lung is a rare entity of unknown etiology and histogenesis. This neoplasm typically presents as an asymptomatic, peripheral, sharply rounded mass in the lung, and histologically composed of large cells with a clear cytoplasm rich in glycogen, blended with an abundant network of sinusoid-type vessels. Immunohistochemical and ultrastructural procedures lead to diagnosis. We describe a primary pulmonary clear cell "sugar" tumor observed in a 28-year-old woman, and give a review of the literature. Clinical aspects, differential diagnosis, therapy and histogenetic aspects are discussed.
ISSN:0761-8417