Alzheimer's disease and coffee: a quantitative review

Purpose: To estimate the pooled risk of coffee consumption for Alzheimer's disease (AD). Material and methods: We have reviewed all observational studies that evaluated the association between AD risk and coffee consumption. Four studies were identified: two case-control studies and two cohorts...

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Bibliographic Details
Published in:Neurological research (New York) 2007-01, Vol.29 (1), p.91-95
Main Authors: Quintana, José Luis Barranco, Allam, Mohamed Farouk, Del Castillo, Amparo Serrano, Navajas, Rafael Fernández-Crehuet
Format: Article
Language:English
Subjects:
Alzheimer Disease - drug therapy
Alzheimer Disease - etiology
Alzheimer Disease - prevention & control
ALZHEIMER'S DISEASE
Case-Control Studies
COFFEE
Cohort Studies
Feeding Behavior - physiology
Humans
META-ANALYSIS
QUANTITATIVE REVIEW
Risk Factors
Surveys and Questionnaires
SYSTEMATIC REVIEW
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Summary:Purpose: To estimate the pooled risk of coffee consumption for Alzheimer's disease (AD). Material and methods: We have reviewed all observational studies that evaluated the association between AD risk and coffee consumption. Four studies were identified: two case-control studies and two cohorts. These studies were carried out between 1990 and 2002. Results: There was an obvious protective effect of coffee consumption in the pooled estimate [risk estimate: 0.73 (95% confidence interval: 0.58-0.92)]. However, the homogeneity test was highly significant (p
ISSN:0161-6412
1743-1328
DOI:10.1179/174313206X152546