Infective endocarditis due to community-associated methicillin-resistant Staphylococcus aureus in injection drug users may be associated with Panton-Valentine leukocidin-negative strains

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates that cause infective endocarditis in injection drug users (IDUs) are distinct from CA-MRSA strains that cause endocardial infection as a complication of skin and soft tissue infections. We present a case of CA-MRSA i...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 2007, Vol.39 (4), p.299-302
Main Authors: Tsigrelis, Constantine, Armstrong, Matthew D., Vlahakis, Nicholas E., Batsis, John A., Baddour, Larry M.
Format: Article
Language:English
Subjects:
Adult
Bacterial diseases
Biological and medical sciences
Cardiology. Vascular system
Community-Acquired Infections - microbiology
Drug addictions
Endocardial and cardiac valvular diseases
Endocarditis, Bacterial - drug therapy
Endocarditis, Bacterial - microbiology
Endocarditis, Bacterial - surgery
Heart
Human bacterial diseases
Humans
Infectious diseases
Male
Medical sciences
Methicillin Resistance
Staphylococcal Infections - drug therapy
Staphylococcal Infections - microbiology
Staphylococcal Infections - surgery
Staphylococcal infections, streptococcal infections, pneumococcal infections
Staphylococcus aureus
Staphylococcus aureus - classification
Staphylococcus aureus - drug effects
Staphylococcus aureus - pathogenicity
Substance Abuse, Intravenous - microbiology
Toxicology
Tricuspid Valve - microbiology
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Summary:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates that cause infective endocarditis in injection drug users (IDUs) are distinct from CA-MRSA strains that cause endocardial infection as a complication of skin and soft tissue infections. We present a case of CA-MRSA infective endocarditis, review pertinent cases previously published, and describe the molecular characteristics of strains from IDUs and patients with skin and soft tissue infections.
ISSN:0036-5548
1651-1980
DOI:10.1080/00365540601003803