Lipopolysaccharide-induced apoptosis of olfactory receptor neurons in rats

Conclusion: Daily intranasal perfusion of lipopolysaccharide (LPS) for 14 days in rats induced apoptosis of olfactory receptor neurons (ORNs) over >3 but

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Bibliographic Details
Published in:Acta oto-laryngologica 2007, Vol.127 (7), p.748-753
Main Authors: Yagi, Sayaka, Tsukatani, Toshiaki, Yata, Tsuyoshi, Tsukioka, Fusae, Miwa, Takaki, Furukawa, Mitsuru
Format: Article
Language:English
Subjects:
Administration, Intranasal
Animals
Antibodies - immunology
apoptosis
Apoptosis - drug effects
bcl-2-Associated X Protein - immunology
bcl-2-Associated X Protein - metabolism
Biological and medical sciences
Caspase 3 - immunology
Caspase 3 - metabolism
DNA, Single-Stranded - immunology
DNA, Single-Stranded - metabolism
Escherichia coli
Female
Immunohistochemistry
lipopolysaccharide
Lipopolysaccharides - pharmacology
Medical sciences
Nasal Mucosa - metabolism
olfactory receptor neurons
Olfactory Receptor Neurons - pathology
Otorhinolaryngology. Stomatology
Proto-Oncogene Proteins c-bcl-2 - immunology
Proto-Oncogene Proteins c-bcl-2 - metabolism
Rats
Rats, Sprague-Dawley
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Description
Summary:Conclusion: Daily intranasal perfusion of lipopolysaccharide (LPS) for 14 days in rats induced apoptosis of olfactory receptor neurons (ORNs) over >3 but
ISSN:0001-6489
1651-2251
DOI:10.1080/00016480601002062