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POLYMORPHISMS OF ANDROGEN RECEPTOR GENE IN CHILDHOOD AND ADOLESCENT MALES WITH FIRST-ONSET MAJOR DEPRESSIVE DISORDER AND ASSOCIATION WITH RELATED SYMPTOMATOLOGY
This study was designed to explore the association between CAG repeats in AR gene and major depressive disorder (MDD) in male children and adolescents. The results showed that there were differences between adolescent depressive patients and adolescent controls in CAG repeats' length and allele...
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| Published in: | International journal of neuroscience 2007-07, Vol.117 (7), p.903-917 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c435t-dc78312351a889174170d738af08308f2d080e218154b04238b4c4381e1582bc3 |
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| cites | cdi_FETCH-LOGICAL-c435t-dc78312351a889174170d738af08308f2d080e218154b04238b4c4381e1582bc3 |
| container_end_page | 917 |
| container_issue | 7 |
| container_start_page | 903 |
| container_title | International journal of neuroscience |
| container_volume | 117 |
| creator | SU, QIAO-RONG SU, LIN-YAN SU, HONG-RI CHEN, QING REN, GUANG-YUAN YIN, YOU SHEN, SHAO-QING YU, AI-YUE XIA, GUO-YUAN |
| description | This study was designed to explore the association between CAG repeats in AR gene and major depressive disorder (MDD) in male children and adolescents. The results showed that there were differences between adolescent depressive patients and adolescent controls in CAG repeats' length and alleles' distributions, and the severity of depression and anxiety was negatively correlated with the length of CAG repeats in adolescent patients. This suggested that AR gene might be involved in the depressive upset in adolescents, and the age- and sex-related prevalent differences might also be associated to CAG repeats. |
| doi_str_mv | 10.1080/00207450600910689 |
| format | article |
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The results showed that there were differences between adolescent depressive patients and adolescent controls in CAG repeats' length and alleles' distributions, and the severity of depression and anxiety was negatively correlated with the length of CAG repeats in adolescent patients. 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This suggested that AR gene might be involved in the depressive upset in adolescents, and the age- and sex-related prevalent differences might also be associated to CAG repeats.</description><subject>Adolescent</subject><subject>Age Distribution</subject><subject>CAG repeat</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>children</subject><subject>Chinese population</subject><subject>Depressive Disorder, Major - genetics</subject><subject>Depressive Disorder, Major - psychology</subject><subject>first-onset major depressive disorder</subject><subject>Gene Frequency</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Male</subject><subject>Polymorphism, Genetic</subject><subject>Receptors, Androgen - genetics</subject><subject>Reference Values</subject><subject>Severity of Illness Index</subject><subject>Trinucleotide Repeats - genetics</subject><issn>0020-7454</issn><issn>1563-5279</issn><issn>1543-5245</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNqFkc2K2zAQgE1p6YbtPkAvRafe3OrHPzLtxdjKWottBcttycnItsymOPGunFD2bfqoq-BAKYXtSRrN982IGcd5j-AnBCn8DCGGoefDAMIIwYBGr5wV8gPi-jiMXjurc961gHfl3MzzrrUxiSJM6VvnCoUBIgh6K-f3RuTbQlSbjMtCArEGcZlW4paVoGIJ29SiAjZggJcgyXieZkKkZwbEqciZTFhZgyK2N_CD1xlY80rWriglOz_fWTtlm4pJyb8zkHIpqpRViy-lSHhcc1EuasXyuGYpkNvCti3iWuTidvvOeTOocdY3l_Pa-bZmdZK5NsmTOHc7j_hHt-9CShAmPlKURij0UAj7kFA1QEogHXBvZ6Yxosj3WuhhQlvPmhRp5FPcduTa-bjUfTDT40nPx2a_mzs9juqgp9PchDCIMI7C_4Io8jEOCLIgWsDOTPNs9NA8mN1emacGwea8wuafFVrnw6X4qd3r_o9xWZgFvi7A7jBMZq9-TWbsm6N6GiczGHXodnNDXqr_5S_9XqvxeN8po5uf08kc7IRf-N0zqsmtAA</recordid><startdate>20070701</startdate><enddate>20070701</enddate><creator>SU, QIAO-RONG</creator><creator>SU, LIN-YAN</creator><creator>SU, HONG-RI</creator><creator>CHEN, QING</creator><creator>REN, GUANG-YUAN</creator><creator>YIN, YOU</creator><creator>SHEN, SHAO-QING</creator><creator>YU, AI-YUE</creator><creator>XIA, GUO-YUAN</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20070701</creationdate><title>POLYMORPHISMS OF ANDROGEN RECEPTOR GENE IN CHILDHOOD AND ADOLESCENT MALES WITH FIRST-ONSET MAJOR DEPRESSIVE DISORDER AND ASSOCIATION WITH RELATED SYMPTOMATOLOGY</title><author>SU, QIAO-RONG ; SU, LIN-YAN ; SU, HONG-RI ; CHEN, QING ; REN, GUANG-YUAN ; YIN, YOU ; SHEN, SHAO-QING ; YU, AI-YUE ; XIA, GUO-YUAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-dc78312351a889174170d738af08308f2d080e218154b04238b4c4381e1582bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Age Distribution</topic><topic>CAG repeat</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>children</topic><topic>Chinese population</topic><topic>Depressive Disorder, Major - genetics</topic><topic>Depressive Disorder, Major - psychology</topic><topic>first-onset major depressive disorder</topic><topic>Gene Frequency</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Male</topic><topic>Polymorphism, Genetic</topic><topic>Receptors, Androgen - genetics</topic><topic>Reference Values</topic><topic>Severity of Illness Index</topic><topic>Trinucleotide Repeats - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SU, QIAO-RONG</creatorcontrib><creatorcontrib>SU, LIN-YAN</creatorcontrib><creatorcontrib>SU, HONG-RI</creatorcontrib><creatorcontrib>CHEN, QING</creatorcontrib><creatorcontrib>REN, GUANG-YUAN</creatorcontrib><creatorcontrib>YIN, YOU</creatorcontrib><creatorcontrib>SHEN, SHAO-QING</creatorcontrib><creatorcontrib>YU, AI-YUE</creatorcontrib><creatorcontrib>XIA, GUO-YUAN</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SU, QIAO-RONG</au><au>SU, LIN-YAN</au><au>SU, HONG-RI</au><au>CHEN, QING</au><au>REN, GUANG-YUAN</au><au>YIN, YOU</au><au>SHEN, SHAO-QING</au><au>YU, AI-YUE</au><au>XIA, GUO-YUAN</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>POLYMORPHISMS OF ANDROGEN RECEPTOR GENE IN CHILDHOOD AND ADOLESCENT MALES WITH FIRST-ONSET MAJOR DEPRESSIVE DISORDER AND ASSOCIATION WITH RELATED SYMPTOMATOLOGY</atitle><jtitle>International journal of neuroscience</jtitle><addtitle>Int J Neurosci</addtitle><date>2007-07-01</date><risdate>2007</risdate><volume>117</volume><issue>7</issue><spage>903</spage><epage>917</epage><pages>903-917</pages><issn>0020-7454</issn><eissn>1563-5279</eissn><eissn>1543-5245</eissn><abstract>This study was designed to explore the association between CAG repeats in AR gene and major depressive disorder (MDD) in male children and adolescents. 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| fulltext | fulltext |
| identifier | ISSN: 0020-7454 |
| ispartof | International journal of neuroscience, 2007-07, Vol.117 (7), p.903-917 |
| issn | 0020-7454 1563-5279 1543-5245 |
| language | eng |
| recordid | cdi_pubmed_primary_17613104 |
| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Adolescent Age Distribution CAG repeat Case-Control Studies Child children Chinese population Depressive Disorder, Major - genetics Depressive Disorder, Major - psychology first-onset major depressive disorder Gene Frequency Genetic Predisposition to Disease Humans Male Polymorphism, Genetic Receptors, Androgen - genetics Reference Values Severity of Illness Index Trinucleotide Repeats - genetics |
| title | POLYMORPHISMS OF ANDROGEN RECEPTOR GENE IN CHILDHOOD AND ADOLESCENT MALES WITH FIRST-ONSET MAJOR DEPRESSIVE DISORDER AND ASSOCIATION WITH RELATED SYMPTOMATOLOGY |
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