Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn

A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ult...

Full description

Saved in:
Bibliographic Details
Published in:Gynecological endocrinology 2007-10, Vol.23 (10), p.581-583
Main Authors: Bertalan, Rita, Csabay, Laszlo, Blazovics, Anna, Rigo, Janos, Varga, Ibolya, Halasz, Zita, Toldy, Erzsebet, Boyle, Belema, Racz, Karoly
Format: Article
Language:English
Subjects:
Adult
Androstenedione - metabolism
Aromatase - metabolism
aromatase activity
Estradiol - metabolism
Female
Fetal Development - physiology
Hirsutism - complications
Humans
Hyperandrogenism - complications
Hyperandrogenism - pathology
Infant, Newborn
Maternal hyperandrogenism
Polycystic Ovary Syndrome - complications
Pregnancy
Pregnancy Complications
testosterone
Testosterone - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ultrasound showed no evidence of adrenal or ovarian masses. She delivered a female newborn with normal female external genitalia. Umbilical cord hormone levels were normal, except for a modest increase of serum testosterone. After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved.
ISSN:0951-3590
1473-0766
DOI:10.1080/09513590701553571