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Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn
A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ult...
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| Published in: | Gynecological endocrinology 2007-10, Vol.23 (10), p.581-583 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c431t-1776e18c4c5c82393e5e222e14ab0ea8648ef2057e61540db031fabd70156a33 |
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| cites | cdi_FETCH-LOGICAL-c431t-1776e18c4c5c82393e5e222e14ab0ea8648ef2057e61540db031fabd70156a33 |
| container_end_page | 583 |
| container_issue | 10 |
| container_start_page | 581 |
| container_title | Gynecological endocrinology |
| container_volume | 23 |
| creator | Bertalan, Rita Csabay, Laszlo Blazovics, Anna Rigo, Janos Varga, Ibolya Halasz, Zita Toldy, Erzsebet Boyle, Belema Racz, Karoly |
| description | A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ultrasound showed no evidence of adrenal or ovarian masses. She delivered a female newborn with normal female external genitalia. Umbilical cord hormone levels were normal, except for a modest increase of serum testosterone. After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved. |
| doi_str_mv | 10.1080/09513590701553571 |
| format | article |
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Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ultrasound showed no evidence of adrenal or ovarian masses. She delivered a female newborn with normal female external genitalia. Umbilical cord hormone levels were normal, except for a modest increase of serum testosterone. After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved.</description><identifier>ISSN: 0951-3590</identifier><identifier>EISSN: 1473-0766</identifier><identifier>DOI: 10.1080/09513590701553571</identifier><identifier>PMID: 17852424</identifier><identifier>CODEN: GYENER</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adult ; Androstenedione - metabolism ; Aromatase - metabolism ; aromatase activity ; Estradiol - metabolism ; Female ; Fetal Development - physiology ; Hirsutism - complications ; Humans ; Hyperandrogenism - complications ; Hyperandrogenism - pathology ; Infant, Newborn ; Maternal hyperandrogenism ; Polycystic Ovary Syndrome - complications ; Pregnancy ; Pregnancy Complications ; testosterone ; Testosterone - metabolism</subject><ispartof>Gynecological endocrinology, 2007-10, Vol.23 (10), p.581-583</ispartof><rights>2007 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2007</rights><rights>Copyright Taylor & Francis Ltd. Oct 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-1776e18c4c5c82393e5e222e14ab0ea8648ef2057e61540db031fabd70156a33</citedby><cites>FETCH-LOGICAL-c431t-1776e18c4c5c82393e5e222e14ab0ea8648ef2057e61540db031fabd70156a33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17852424$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bertalan, Rita</creatorcontrib><creatorcontrib>Csabay, Laszlo</creatorcontrib><creatorcontrib>Blazovics, Anna</creatorcontrib><creatorcontrib>Rigo, Janos</creatorcontrib><creatorcontrib>Varga, Ibolya</creatorcontrib><creatorcontrib>Halasz, Zita</creatorcontrib><creatorcontrib>Toldy, Erzsebet</creatorcontrib><creatorcontrib>Boyle, Belema</creatorcontrib><creatorcontrib>Racz, Karoly</creatorcontrib><title>Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn</title><title>Gynecological endocrinology</title><addtitle>Gynecol Endocrinol</addtitle><description>A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. 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After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved.</description><subject>Adult</subject><subject>Androstenedione - metabolism</subject><subject>Aromatase - metabolism</subject><subject>aromatase activity</subject><subject>Estradiol - metabolism</subject><subject>Female</subject><subject>Fetal Development - physiology</subject><subject>Hirsutism - complications</subject><subject>Humans</subject><subject>Hyperandrogenism - complications</subject><subject>Hyperandrogenism - pathology</subject><subject>Infant, Newborn</subject><subject>Maternal hyperandrogenism</subject><subject>Polycystic Ovary Syndrome - complications</subject><subject>Pregnancy</subject><subject>Pregnancy Complications</subject><subject>testosterone</subject><subject>Testosterone - metabolism</subject><issn>0951-3590</issn><issn>1473-0766</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNp9kc1u1TAQhS0EopfCA7BBFovuAnZsx4lgg6ryIxWx6T6aOJNcV459sZNW4Q14axzdK_EnWFkjf-do5hxCnnP2irOavWaN4kI1TDOulFCaPyA7LrUomK6qh2S3_RcbcEaepHTLGBdSl4_JGde1KmUpd-T7Z5gxenB0vx4wgu9jGNHbNNEOR-u99SMdYpgoQnQrPUQcPXiz0ozmKYwRU9qgxc_W0R6dvcO40j5goj7MG9MvBumdjdbZbzDb4GkYKNABJ3BIPd53Ifqn5NEALuGz03tObt5f3Vx-LK6_fPh0-e66MFLwueBaV8hrI40ydSkagQrLskQuoWMIdSVrHEqmNFZcSdZ3TPABun7LqAIhzsnF0Tbv9XXBNLeTTQadA49hSW3V5JQqpjL48g_wNixbUqnljZai1qrOED9CJoaUIg7tIdoJ4tpy1m4dtX91lDUvTsZLN2H_U3EqJQNvj4D1Q4gT3Ifo-naG1YU45IqMTa34n_-b3-R7BDfvDUT85YJ_qn8AdeSz1Q</recordid><startdate>20071001</startdate><enddate>20071001</enddate><creator>Bertalan, Rita</creator><creator>Csabay, Laszlo</creator><creator>Blazovics, Anna</creator><creator>Rigo, Janos</creator><creator>Varga, Ibolya</creator><creator>Halasz, Zita</creator><creator>Toldy, Erzsebet</creator><creator>Boyle, Belema</creator><creator>Racz, Karoly</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20071001</creationdate><title>Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn</title><author>Bertalan, Rita ; 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| fulltext | fulltext |
| identifier | ISSN: 0951-3590 |
| ispartof | Gynecological endocrinology, 2007-10, Vol.23 (10), p.581-583 |
| issn | 0951-3590 1473-0766 |
| language | eng |
| recordid | cdi_pubmed_primary_17852424 |
| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Adult Androstenedione - metabolism Aromatase - metabolism aromatase activity Estradiol - metabolism Female Fetal Development - physiology Hirsutism - complications Humans Hyperandrogenism - complications Hyperandrogenism - pathology Infant, Newborn Maternal hyperandrogenism Polycystic Ovary Syndrome - complications Pregnancy Pregnancy Complications testosterone Testosterone - metabolism |
| title | Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn |
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