Potential neuropsychological profiles in welders occupationally exposed to manganese: An examination of effect size patterns

This study used effect sizes to examine two recently published articles by Bowler et al. (2003 , 2006 ) that purport to show that welders who had been occupationally exposed to manganese demonstrate a specific pattern of neuropsychological impairment. In the two articles, the welding groups were com...

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Bibliographic Details
Published in:Journal of clinical and experimental neuropsychology 2007-11, Vol.29 (8), p.813-822
Main Authors: Rohling, Martin L., Demakis, George J.
Format: Article
Language:English
Subjects:
Analysis of Variance
Biological and medical sciences
Case-Control Studies
Chemical and industrial products toxicology. Toxic occupational diseases
Data Interpretation, Statistical
Humans
Manganese Poisoning - complications
Medical sciences
Mental Disorders - chemically induced
Metals and various inorganic compounds
Nervous System Diseases - chemically induced
Neuropsychological Tests - statistics & numerical data
Occupational Diseases - complications
Occupational Exposure - adverse effects
Reference Values
Research Design - standards
Sample Size
Statistics, Nonparametric
Toxicology
Welding
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Summary:This study used effect sizes to examine two recently published articles by Bowler et al. (2003 , 2006 ) that purport to show that welders who had been occupationally exposed to manganese demonstrate a specific pattern of neuropsychological impairment. In the two articles, the welding groups were composed of different participants, but the control group was composed of the same participants in both studies. A similar neuropsychological battery was administered across studies. Effect size differences between welders and controls were quite different across both studies, and the pattern of effect sizes within each study for neuropsychological domains was different. Taken together, these articles do not support the claim that chronic manganese exposure in welders results in a specific and identified pattern of neuropsychological impairment.
ISSN:1380-3395
1744-411X
DOI:10.1080/13803390601087072