introduction to metabolomics and its potential application in veterinary science

Metabolomics has been found to be applicable to a wide range of fields, including the study of gene function, toxicology, plant sciences, environmental analysis, clinical diagnostics, nutrition, and the discrimination of organism genotypes. This approach combines high-throughput sample analysis with...

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Bibliographic Details
Published in:Comparative medicine 2007-10, Vol.57 (5), p.436-442
Main Authors: Jones, O.A.H, Cheung, V.L
Format: Article
Language:English
Subjects:
analytical methods
Animal Diseases - drug therapy
Animal Diseases - metabolism
animal use reduction
Animals
Chromatography, Liquid
drug discovery
Gas Chromatography-Mass Spectrometry
Metabolism
metabolome
metabolomics
Nuclear Magnetic Resonance, Biomolecular
pharmacology
toxicology
veterinary drugs
veterinary medicine
Veterinary Medicine - methods
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Summary:Metabolomics has been found to be applicable to a wide range of fields, including the study of gene function, toxicology, plant sciences, environmental analysis, clinical diagnostics, nutrition, and the discrimination of organism genotypes. This approach combines high-throughput sample analysis with computer-assisted multivariate pattern-recognition techniques. It is increasingly being deployed in toxico- and pharmacokinetic studies in the pharmaceutical industry, especially during the safety assessment of candidate drugs in human medicine. However, despite the potential of this technique to reduce both costs and the numbers of animals used for research, examples of the application of metabolomics in veterinary research are, thus far, rare. Here we give an introduction to metabolomics and discuss its potential in the field of veterinary science.
ISSN:1532-0820
2769-819X