A case of recurrent bilateral pneumonia with fever. Diagnosis: microscopic polyangiitis

Microscopic polyangiitis (MPA) is a rare systemic disease that usually presents as a pulmonary-renal syndrome. We describe 35-year-old men who presented with hemoptysis and bilateral alveolar opacities of the upper part of both lungs. The CT scan showed alveolar and round-glass opacities with a &quo...

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Bibliographic Details
Published in:Revue de pneumologie clinique 2007-12, Vol.63 (6), p.384
Main Authors: Msaad, S, Yangui, I, Ben Amira, S, Kammoun, K, Boudawara, T, Ayoub, A
Format: Article
Language:fre
Subjects:
Adult
Fever - etiology
Humans
Male
Pneumonia - etiology
Pulmonary Fibrosis - diagnosis
Recurrence
Vasculitis - diagnosis
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Summary:Microscopic polyangiitis (MPA) is a rare systemic disease that usually presents as a pulmonary-renal syndrome. We describe 35-year-old men who presented with hemoptysis and bilateral alveolar opacities of the upper part of both lungs. The CT scan showed alveolar and round-glass opacities with a "mosaic-like" pattern. Bronchoalveolar lavage confirmed pulmonary hemorrhage. Renal biopsy was indicated because proteinuria revealed extracapillary glomerulonephritis. Laboratory tests showed a high level of serum antimyeloperoxidase-antineutrophil cytoplasmic antibody. We made a diagnosis of MPA. Cyclophosphamide and corticosteroid therapy was instituted and remission achieved. Through this case report, we discuss the diversity of the radio-clinical features of MPA.
ISSN:0761-8417