Estimation of the Local Statistical Noise in Emission Computed Tomography

A simple modification of the filtered backprojection algorithm is presented for the computation of the local statistical noise in emission computed tomography. The technique is general in that any distribution of radioactivity may be accommodated. When applied to positron emission tomography, it is...

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Bibliographic Details
Published in:IEEE transactions on medical imaging 1982, Vol.1 (2), p.142-146
Main Authors: Alpert, N. M., Chesler, D. A., Correia, J. A., Ackerman, R. H., Chang, J. Y., Finklestein, S., Davis, S. M., Brownell, G. L., Taveras, J. M.
Format: Article
Language:English
Subjects:
Computed tomography
Detectors
Electromagnetic scattering
Electromagnetic wave absorption
Event detection
Particle scattering
Positron emission tomography
Radioactive decay
Single photon emission computed tomography
Spatial resolution
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Summary:A simple modification of the filtered backprojection algorithm is presented for the computation of the local statistical noise in emission computed tomography. The technique is general in that any distribution of radioactivity may be accommodated. When applied to positron emission tomography, it is shown that the effects of photon absorption, random coincidences, radioactive decay, and detector nonuniformity may be included. Calculations have shown the effects of resolution, object size, and photon absorption on the statistical noise of disk-shaped emitters. Comparison of calculation and experiment show close agreement both in magnitude and spatial variation. Measurements of the noise level in tomograms of the brain obtained during continuous inhalation of 150-CO2 demonstrate that estimates of radioactivity concentration with a precision of a few percent are readily attainable.
ISSN:0278-0062
1558-254X
DOI:10.1109/TMI.1982.4307561