Clinical Characteristics Associated with Isolation of Small-Colony Variants of Staphylococcus aureus and Pseudomonas aeruginosa from Respiratory Secretions of Patients with Cystic Fibrosis

During a 3-month period, small-colony variant phenotypes of both Staphylococcus aureus and Pseudomonas aeruginosa were isolated from respiratory secretions of 8.2% and 9.2%, respectively, of 98 patients with cystic fibrosis, particularly those with advanced pulmonary disease and prolonged antibiotic...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2008-05, Vol.46 (5), p.1832-1834
Main Authors: Schneider, Michael, Mühlemann, Kathrin, Droz, Sara, Couzinet, Sabine, Casaulta, Carmen, Zimmerli, Stefan
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-Bacterial Agents - therapeutic use
Bacteriology
Carrier State - microbiology
Child
Child, Preschool
Cystic Fibrosis - complications
Humans
Infant
Pseudomonas aeruginosa
Pseudomonas aeruginosa - growth & development
Pseudomonas aeruginosa - isolation & purification
Pseudomonas Infections - microbiology
Pseudomonas Infections - pathology
Pseudomonas Infections - physiopathology
Respiratory System - microbiology
Respiratory System - secretion
Staphylococcal Infections - microbiology
Staphylococcal Infections - pathology
Staphylococcal Infections - physiopathology
Staphylococcus aureus
Staphylococcus aureus - growth & development
Staphylococcus aureus - isolation & purification
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Summary:During a 3-month period, small-colony variant phenotypes of both Staphylococcus aureus and Pseudomonas aeruginosa were isolated from respiratory secretions of 8.2% and 9.2%, respectively, of 98 patients with cystic fibrosis, particularly those with advanced pulmonary disease and prolonged antibiotic exposure.
ISSN:0095-1137
1098-660X
1098-5530
DOI:10.1128/JCM.00361-08