Heterotopic ossification - from the aetiology to the current management

Heterotopic ossifications (HO) are defined as the abnormal formation of bone in soft tissues. It can be classified into acquired and congenital forms. The acquired form, of which the pathogenesis is not fully understood, is often diagnosed in patients with traumatic brain injury, spinal cord injury,...

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Bibliographic Details
Published in:Der Unfallchirurg 2008-07, Vol.111 (7), p.523
Main Authors: Gautschi, O P, Cadosch, D, Bauer, S, Filgueira, L, Zellweger, R
Format: Article
Language:ger
Subjects:
Anti-Inflammatory Agents - administration & dosage
Diagnostic Imaging - methods
Humans
Ossification, Heterotopic - diagnosis
Ossification, Heterotopic - therapy
Osteotomy - methods
Radiotherapy - methods
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Summary:Heterotopic ossifications (HO) are defined as the abnormal formation of bone in soft tissues. It can be classified into acquired and congenital forms. The acquired form, of which the pathogenesis is not fully understood, is often diagnosed in patients with traumatic brain injury, spinal cord injury, musculo-skeletal trauma or injuries associated with burns. HO presents itself mostly asymptomatically, the symptoms of the initial stadium are often unspecific; however, severe forms can lead to severe disability. Imaging techniques, foremost bone szintigraphy, are mostly used for verification of the diagnosis. Local radiotherapy and nonsteroidal anti-inflammatory drugs are the classical therapeutic and prophylactic options. In advanced stages, surgical resection may be required.
ISSN:0177-5537
DOI:10.1007/s00113-008-1475-z