Asymptomatic Hyperuricemia: Impact of Ultrasonography

Thirty-five patients (23 males) with asymptomatic hyperuricemia for at least two years underwent two-dimensioal ultrasonography of knees and ankles. Urate deposits (tophi) in tendons, synovium, and other soft tissues were detected in 12 patients (34%). Increased vascularity (inflammation) was eviden...

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Bibliographic Details
Published in:Nucleosides, nucleotides & nucleic acids nucleotides & nucleic acids, 2008-06, Vol.27 (6-7), p.592-595
Main Authors: Puig, J. G., de Miguel, E., Castillo, M. C., Rocha, A. López, Martínez, M. A., Torres, R. J.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Female
gout
Gout - complications
Gout - diagnostic imaging
Gout - metabolism
Gout - pathology
Humans
hyperuricemia
Hyperuricemia - complications
Hyperuricemia - diagnostic imaging
Hyperuricemia - metabolism
Hyperuricemia - pathology
Inflammation - complications
Inflammation - diagnostic imaging
Inflammation - metabolism
Inflammation - pathology
Male
Middle Aged
tophus
Ultrasonography
Uric acid
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Summary:Thirty-five patients (23 males) with asymptomatic hyperuricemia for at least two years underwent two-dimensioal ultrasonography of knees and ankles. Urate deposits (tophi) in tendons, synovium, and other soft tissues were detected in 12 patients (34%). Increased vascularity (inflammation) was evident in 8 of these patients (23%). Tophi were more frequently found in knees than in ankles and were especially prevalent in the distal patellar tendon. The presence of tophi was unrelated to the known duration of hyperuricemia (mean, 5 years). Ultrasonography allows detection of tophi and inflammation in a third and in a fourth, respectively, of asymptomatic hyperuricemic patients.
ISSN:1525-7770
1532-2335
DOI:10.1080/15257770802136040