Prognostic factors for oral squamous cell carcinoma

The aim of the present study was to analyze different prognostic factors to calculate the overall survival in oral squamous cell carcinoma (OSCC). Samples retrospectively collected from 99 patients with primary OSCC were analyzed with regard to tumor node metastasis stage, grading, and 5-year surviv...

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Bibliographic Details
Published in:Chirurg 2009-02, Vol.80 (2), p.138
Main Authors: Eckert, A W, Lautner, M H W, Dempf, R, Schubert, J, Bilkenroth, U
Format: Article
Language:ger
Subjects:
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Cause of Death
Databases, Factual
Female
Germany
Humans
Lymphatic Metastasis - pathology
Male
Mathematical Computing
Middle Aged
Mouth Neoplasms - mortality
Mouth Neoplasms - pathology
Mouth Neoplasms - surgery
Neoplasm Staging
Prognosis
Retrospective Studies
Survival Rate
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Summary:The aim of the present study was to analyze different prognostic factors to calculate the overall survival in oral squamous cell carcinoma (OSCC). Samples retrospectively collected from 99 patients with primary OSCC were analyzed with regard to tumor node metastasis stage, grading, and 5-year survival time and summarized at an SPSS 11.0 databank. Treated were 72 men and 27 women (average age 59 years) due to oral squamous cell carcinoma. A general 5-year survival time of 57.3% was found. Patient survival depended on tumor size and the extent of lymph node metastasis: survival was 80.1% (n=23) for T1 tumors and only 16.2% (n=28) for T4 tumors, 68.7% (n=55) at the N0 stage and 42.8% at >N0 (n=44, chi(2) test P=0.01, Fischer's exact test P=0.014). Highly differentiated carcinomas (n=26) had a survival probability of 78.9% and G2 and G3 tumors of only 48.9% (n=73, chi(2) test P
ISSN:1433-0385
DOI:10.1007/s00104-008-1647-y