Fructose-amino acid conjugate and other constituents from Cyperus rotundus L

• Published in: Natural product research 2008-11, Vol.22 (17), p.1487-1497
• Main Authors: Sayed, Hanaa M., Mohamed, Mahmoud H., Farag, Salwa F., Mohamed, Gamal A., Omobuwajo, Olanrewaju R.M., Proksch, Peter
• Format: Article
• Language: English
• Subjects: alpha-Amylases - antagonists & inhibitors; Amino Acids - chemistry; Amino Acids - isolation & purification; Amino Acids - pharmacology; antioxidant and α-amylase inhibitory activities; Antioxidants - chemistry; Antioxidants - isolation & purification; Antioxidants - pharmacology; Apigenin; Cyperaceae; Cyperus - chemistry; Cyperus rotundus L; Flavonoids; Fructose - analogs & derivatives; Fructose - chemistry; Fructose - isolation & purification; fructose-amino acid conjugate; Glucosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; phenolic compounds; Plants, Medicinal - chemistry; Stereoisomerism
• ISSN: 1478-6419; 1478-6427
• DOI: 10.1080/14786410802038556

Further phytochemical study on the aerial parts of Cyperus rotundus L. led to the isolation of a fructose-amino acid conjugate, N-(1-deoxy-α-D-fructos-1-yl)-L-tryptophan (16) and its tautomers, in addition to n-butyl-β-D-fructopyranoside (1), ethyl-α-D-glucopyranoside (2), adenosine (3), (−)-(E)-caffeoylmalic acid (4), vitexin (5), isovitexin (6), orientin (7), epiorientin (8), myricetin 3-O-β-D-galactopyranoside (9), luteolin 7-O-β-D-glucuronopyranoside-6″-methyl ester (10), chlorogenic acid (11), luteolin 4′-O-β-D-glucuronopyranoside (12), luteolin 7-O-β-D-glucuronopyranoside (13), uridine (14) and ellagic acid (15). Their structures were elucidated on the basis of spectroscopic methods. Additionally, antioxidant and α-amylase inhibitory activities of some of the isolated phenolic compounds were carried out.