A pilot study on the usefulness of body mass index and waist hip ratio as a predictive tool for gestational diabetes in Asian Indians

Gestational diabetes mellitus (GDM) is a common public health issue of pregnancy and women who have had GDM are at high risk for developing of diabetes mellitus Type-2. The aim of this study was to find the association between various clinical and biochemical parameters and GDM. One hundred and six...

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Bibliographic Details
Published in:Gynecological endocrinology 2008-01, Vol.24 (12), p.701-707
Main Authors: Madhavan, Anju, Beena Kumari, R., Sanal, Madhusudana Girija
Format: Article
Language:English
Subjects:
Adolescent
Adult
Birth Weight
Body Mass Index
Diabetes, Gestational - epidemiology
Female
Gestational diabetes
Humans
India - epidemiology
Infant, Newborn
obesity
Obesity - epidemiology
obstetric complications
Pilot Projects
Predictive Value of Tests
Pregnancy
risk determinant
ROC Curve
Sensitivity and Specificity
Waist Circumference
Waist-Hip Ratio
Young Adult
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Summary:Gestational diabetes mellitus (GDM) is a common public health issue of pregnancy and women who have had GDM are at high risk for developing of diabetes mellitus Type-2. The aim of this study was to find the association between various clinical and biochemical parameters and GDM. One hundred and six consecutive patients who attended the out patient unit of department of gynecology, Kottayam Medical College, were enrolled in the study and followed up through the whole antenatal, intra-partum and post-partum periods to identify the obstetric outcome. We found that the prevalence of GDM was seven times higher in those with higher waist-hip ratio (WHR > 0.85) compared with those having a lower WHR (p < 0.001).Those with higher WHR gained more weight than other group (10.6 kg vs. 8.1 kg; p < 0.001). Obesity (BMI ≥23) and higher WHR were associated with increased risk of gestational diabetes (BMI ≥23: OR = 7.5, CI 95% = (1.61-34.31), p = 0.013; WHR > 0.85: OR = 12.05, CI 95% = (1.82-77.43), p = 0.007). We found that a WHR of 0.849 has the optimal sensitivity and specificity for the prediction of GDM. A waist circumference of 85.5 cm (with sensitivity of 75%, specificity 81.4%) and a BMI of 24.3 kg m2 (sensitivity 75%, specificity 86.5%) had the best predictive value. In conclusion, we found that maternal obesity has a strong correlation with obstetric complications. We found WHR is more important risk determinant for GDM in overweight obese women than women with normal weight lean.
ISSN:0951-3590
1473-0766
DOI:10.1080/09513590802444134