Multijoint Reflex Responses to Constant-Velocity Volitional Movements of the Stroke Elbow

• Published in: Journal of neurophysiology 2009-09, Vol.102 (3), p.1398-1410
• Main Authors: Sangani, Samir G, Starsky, Andrew J, McGuire, John R, Schmit, Brian D
• Format: Article
• Language: English
• Subjects: Action Potentials - physiology; Adult; Aged; Analysis of Variance; Elbow - physiopathology; Elbow Joint - physiopathology; Electromyography - methods; Female; Humans; Male; Middle Aged; Movement - physiology; Muscle, Skeletal - physiopathology; Reflex - physiology; Stroke - pathology; Torque; Young Adult
• ISSN: 0022-3077; 1522-1598
• DOI: 10.1152/jn.90972.2008

1 Departments of Biomedical Engineering, 2 Physical Therapy, and 3 Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, Wisconsin Submitted 27 August 2008; accepted in final form 17 June 2009 Abstract Multijoint reflex coupling could impact the voluntary control of functional arm movements in people post stroke. The multijoint responses to active-assist, constant-velocity movements of the elbow joint were measured in 14 individuals post stroke and 9 neurologically intact controls. Resulting responses in the stroke group illustrated a change in the reflex coupling of the elbow and shoulder muscles compared with passive perturbations of the spastic elbow. Voluntary effort during constant-velocity elbow extension resulted in reflex shoulder abduction, differing from the reflex coupling observed between the elbow flexors and shoulder adductors observed during passive elbow extension. These results suggest that post stroke, voluntary drive alters reflex coupling of the elbow and shoulder. Flexion of the elbow during active-assist also resulted in reflex coupling. Shoulder abduction torque decreased with constant-velocity flexion of the elbow; however, no net adduction was observed at the end of the perturbation. Shoulder flexion/extension and internal/external rotation torque responses demonstrated similar modulations to imposed active-assist perturbations of the elbow in subjects post stroke. Responses were absent during passive perturbations of the control elbow; however, shoulder torque modulations were observed during constant-velocity, active-assist tasks. The active-assist response patterns in controls were similar to stroke subjects during the extension task but opposite during flexion of the elbow. This study provides evidence of a neural coupling between elbow and shoulder muscles and a modulation of this coupling during voluntary drive of the spastic arm. Address for reprint requests and other correspondence: B. D. Schmit, Dept. of Biomedical Engineering, Marquette University, P.O. Box 1881, Milwaukee, WI 53201-1881 (E-mail: brian.schmit{at}marquette.edu )