The significance of long acting insulin analogues in the treatment of type 2 diabetes mellitus

Between 5 and 10% of the European population suffers from diabetes, and its prevalence is constantly rising, in Austria like in other countries. The main goals in the treatment of diabetes mellitus are the prevention of complications and organ damage, the prevention of severe hypo- and hyperglycaemi...

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Bibliographic Details
Published in:Wiener Klinische Wochenschrift 2009-07, Vol.121 (13-14), p.473
Main Authors: Ludvik, Bernhard, Brath, Helmut, Wascher, Thomas, Toplak, Hermann
Format: Article
Language:ger
Subjects:
Austria
Body Weight
Cohort Studies
Diabetes Mellitus, Type 2 - drug therapy
Follow-Up Studies
Humans
Hypoglycemia - prevention & control
Hypoglycemic Agents - administration & dosage
Hypoglycemic Agents - economics
Hypoglycemic Agents - therapeutic use
Insulin - administration & dosage
Insulin - agonists
Insulin - analogs & derivatives
Insulin - economics
Insulin - therapeutic use
Insulin Detemir
Insulin Glargine
Insulin, Long-Acting
Myocardial Infarction - epidemiology
Practice Guidelines as Topic
Quality of Life
Randomized Controlled Trials as Topic
Retrospective Studies
Thiazolidinediones - administration & dosage
Thiazolidinediones - economics
Thiazolidinediones - therapeutic use
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Summary:Between 5 and 10% of the European population suffers from diabetes, and its prevalence is constantly rising, in Austria like in other countries. The main goals in the treatment of diabetes mellitus are the prevention of complications and organ damage, the prevention of severe hypo- and hyperglycaemia and the preservation of quality of life. Many patients with type 2 diabetes become insulin-dependent in the course of their disease. The application of a long acting insulin or insulin analogue is the simplest way of initiating an insulin therapy and is in accordance with current guidelines. Current scientific evidence shows that the use of long acting insulin analogues for type 2 diabetes; which can no longer be sufficiently controlled with oral antidiabetic agents, is simple, safe and efficacious. Thus, this treatment option should be available without any restrictions to physicians and patients in order to facilitate the beginning of an insulin regime. This position paper summarises up the current evidence concerning this subject.
ISSN:0043-5325
DOI:10.1007/s00508-009-1209-4