Tradeoffs of integrating real-time tracking into IGRT for prostate cancer treatment

This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution. The current IGRT process includes magnetic...

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Bibliographic Details
Published in:Physics in medicine & biology 2009-09, Vol.54 (17), p.N393-N401
Main Authors: Zhu, X, Bourland, J D, Yuan, Y, Zhuang, T, O'Daniel, J, Thongphiew, D, Wu, Q J, Das, S K, Yoo, S, Yin, F F
Format: Article
Language:English
Subjects:
Cone-Beam Computed Tomography
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Male
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - radiotherapy
Radiotherapy - instrumentation
Radiotherapy - methods
Radiotherapy Planning, Computer-Assisted
Safety
Systems Integration
Time Factors
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Summary:This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution. The current IGRT process includes magnetic resonance imaging (MRI) for prostate delineation, CT simulation for treatment planning, daily on-board kV and CBCT imaging for target alignment, and MRI/MRS for post-treatment assessment. This study assesses (1) magnetic-field-induced displacement and radio-frequency (RF)-induced heating of transponders during MRI at 1.5 T and 3 T, and (2) image artifacts caused by transponders and the detector array in phantom and patient cases with the different imaging systems. A tissue-equivalent phantom mimicking prostate tissue stiffness was constructed and implanted with three operational transponders prior to phantom solidification. The measurements show that the Calypso system is safe with all the imaging systems. Transponder position displacements due to the MR field are minimal (
ISSN:0031-9155
1361-6560
DOI:10.1088/0031-9155/54/17/N03