Effect of Ocimum sanctum on homocysteine levels and lipid profile in healthy rabbits

Context: Ocimum sanctum has been reported to have a variety of medicinal properties. Objective: The present study was planned to evaluate the effect of O. sanctum on plasma homocysteine levels and lipid profile in healthy rabbits. Material and methods: Forty rabbits were divided into two groups (20...

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Bibliographic Details
Published in:Archives of physiology and biochemistry 2011-02, Vol.117 (1), p.8-11
Main Authors: Dahiya, Kiran, Sethi, Jyoti, Dhankhar, Rakesh, Singh, Veena, Singh, Sangeeta B., Yadav, Mridul, Sood, Sushama, Sachdeva, Ashuma
Format: Article
Language:English
Subjects:
Administration, Oral
Animal Feed
Animals
Biological and medical sciences
Blood Glucose - analysis
cardioprotective
Cardiotonic Agents - administration & dosage
Cardiovascular Diseases - diet therapy
Cardiovascular Diseases - prevention & control
Dyslipidemias - diet therapy
Dyslipidemias - prevention & control
Female
Fundamental and applied biological sciences. Psychology
high density lipoprotein
Homocysteine - blood
Hyperhomocysteinemia - diet therapy
Hyperhomocysteinemia - prevention & control
Lipid Metabolism - physiology
Lipoproteins - blood
Male
Ocimum
Plant Leaves
Rabbits
Triglycerides - blood
Tulsi
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Context: Ocimum sanctum has been reported to have a variety of medicinal properties. Objective: The present study was planned to evaluate the effect of O. sanctum on plasma homocysteine levels and lipid profile in healthy rabbits. Material and methods: Forty rabbits were divided into two groups (20 each). Group I rabbits received normal diet and group II rabbits received fresh leaves of O. sanctum (2 g/day) for 8 weeks along with normal diet. Fasting plasma samples were estimated for homocysteine and lipid profile. The results were analysed statistically. Results: The levels of homocysteine, total cholesterol, triglycerides, low density lipoprotein cholesterol, very low density lipoprotein cholesterol were found to be decreased and high density lipoprotein cholesterol levels increased significantly on supplementation with O. sanctum (p 
ISSN:1381-3455
1744-4160
DOI:10.3109/13813455.2010.496855