Application of DNA Fingerprinting to Parentage and Extended Family Relationship Testing

For the purpose of applying DNA fingerprinting to parentage or other extended blood relationship testing, we have developed a general system for estimating blood relationship between a set of individuals. This system can be used for any blood relationship testing, even if critical family members are...

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Bibliographic Details
Published in:Human heredity 1990, Vol.40 (6), p.356-362
Main Authors: Honma, Masamitsu, Ishiyama, Ikuo
Format: Article
Language:English
Subjects:
Bayes Theorem
Biological and medical sciences
DNA Fingerprinting
Family
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Humans
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Summary:For the purpose of applying DNA fingerprinting to parentage or other extended blood relationship testing, we have developed a general system for estimating blood relationship between a set of individuals. This system can be used for any blood relationship testing, even if critical family members are unavailable. A general formula for calculating the probability of such relationships based on Bayes' theorem has been devised and the ability of DNA fingerprinting produced by Jeffreys' polycore probe to determine the relationships has been evaluated.
ISSN:0001-5652
1423-0062
DOI:10.1159/000153959