Mixed tumor of the skin

An 81-year-old woman presented with a skin-colored, slowly growing tumor on her right lower eyelid. The diagnosis of mixed tumor of the skin was confirmed after excision and histologic examination of the tissue, which demonstrated a characteristic histology and immunohistochemistry. The mixed tumor...

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Bibliographic Details
Published in:Hautarzt 2011-09, Vol.62 (9), p.688
Main Authors: Zirbs, M, Konstantinow, A, Ziai, M, Brockow, K, Hein, R, Ring, J
Format: Article
Language:ger
Subjects:
Adenoma, Pleomorphic - diagnosis
Adenoma, Pleomorphic - pathology
Adenoma, Pleomorphic - surgery
Aged, 80 and over
Apocrine Glands - pathology
Biomarkers, Tumor - analysis
Cell Transformation, Neoplastic - pathology
Diagnosis, Differential
Eyelid Neoplasms - diagnosis
Eyelid Neoplasms - pathology
Eyelid Neoplasms - surgery
Female
Humans
Immunohistochemistry
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - surgery
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Description
Summary:An 81-year-old woman presented with a skin-colored, slowly growing tumor on her right lower eyelid. The diagnosis of mixed tumor of the skin was confirmed after excision and histologic examination of the tissue, which demonstrated a characteristic histology and immunohistochemistry. The mixed tumor of the skin is a usually benign neoplasm believed to originate in sweat glands. It is composed of epithelial cells set in a mesenchymal matrix, showing apocrine differentiation. Immunohistochemical staining is positive for cytokeratin, CEA, EMA and S100.
ISSN:1432-1173
DOI:10.1007/s00105-010-2103-8