Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients

The present study evaluated the anti-hyperglycemic and lipid-lowering properties of Emblica officinalis Gaertn. fruit in normal and diabetic human volunteers. The results indicated a significant decrease (P < 0.05) in fasting and 2-h post-prandial blood glucose levels on the 21st day in both norm...

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Bibliographic Details
Published in:International journal of food sciences and nutrition 2011-09, Vol.62 (6), p.609-616
Main Authors: Akhtar, Muhammad Shoaib, Ramzan, Ayesha, Ali, Amanat, Ahmad, Maqsood
Format: Article
Language:English
Subjects:
Adult
Amla fruit
blood glucose
Blood Glucose - metabolism
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - drug therapy
Emblica officinalis Gaertn
Fasting
Female
Food science
Fruit
Fruits
Glucose
Humans
Hypoglycemia
Hypoglycemic Agents - pharmacology
Hypoglycemic Agents - therapeutic use
Hypolipidemic Agents - pharmacology
Hypolipidemic Agents - therapeutic use
lipid profile
Lipids - blood
Lipoproteins
Male
Middle Aged
normal and diabetic human volunteers
Phyllanthus emblica
Phytochemicals
Plant Preparations - pharmacology
Plant Preparations - therapeutic use
Postprandial Period
Reference Values
Triglycerides - blood
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Summary:The present study evaluated the anti-hyperglycemic and lipid-lowering properties of Emblica officinalis Gaertn. fruit in normal and diabetic human volunteers. The results indicated a significant decrease (P < 0.05) in fasting and 2-h post-prandial blood glucose levels on the 21st day in both normal and diabetic subjects receiving 1, 2 or 3 g E. officinalis powder per day as compared with their baseline values. Significant (P < 0.05) decreases were also observed in total cholesterol and triglycerides in both normal and diabetic volunteers on day 21 that were given either 2 or 3 g E. officinalis powder per day. However, diabetic volunteers receiving only 3 g E. officinalis powder exhibited a significant (P < 0.05) decrease in total lipids on day 21. Both normal and diabetic volunteers receiving 2 or 3 g E. officinalis powder significantly (P < 0.05) improved high-density lipoprotein-cholesterol and lowered low-density lipoprotein-cholesterol levels.
ISSN:0963-7486
1465-3478
DOI:10.3109/09637486.2011.560565