Rapid Development of Intestinal Type Gastric Adenocarcinoma

Intestinal type gastric adenocarcinoma is felt to develop over a protracted time period through a series of defined steps. Several potential risk factors for the development of gastric cancer have been identified, including a family history of gastric cancer and Helicobacter pylori infection. We pre...

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Bibliographic Details
Published in:Case reports in gastroenterology 2011-04, Vol.5 (1), p.192-195
Main Authors: Oh, Young S., Massey, Benson T.
Format: Article
Language:English
Subjects:
Atrophic gastritis
Endoscopic ultrasonography
Gastric cancer
Metaplasia
Published: April 2011
Citations: Items that this one cites
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Description
Summary:Intestinal type gastric adenocarcinoma is felt to develop over a protracted time period through a series of defined steps. Several potential risk factors for the development of gastric cancer have been identified, including a family history of gastric cancer and Helicobacter pylori infection. We present the case of a patient with neither risk factor who progressed in a 14 month time frame from histologically normal gastric mucosa to early stage intestinal type gastric adenocarcinoma in the setting of diffuse gastric intestinal metaplasia and atrophic gastritis. This patient’s presentation conflicts with our current understanding of the development of intestinal type gastric adenocarcinoma.
ISSN:1662-0631
1662-0631
DOI:10.1159/000326960