Relationship between processed total motile sperm count of husband or donor semen and pregnancy outcome following intrauterine insemination

• Published in: Systems biology in reproductive medicine 2011-10, Vol.57 (5), p.251-255
• Main Authors: Dong, Fang li, Sun, Ying pu, Su, Ying chun, Guo, Yi hong, Hu, Lin li, Wang, Fang
• Format: Article
• Language: English
• Subjects: artificial insemination; Female; Humans; Insemination, Artificial; Male; Pregnancy; Pregnancy Outcome; processed total motile sperm count; Retrospective Studies; Sperm Count; Sperm Motility; Tissue Donors
• ISSN: 1939-6368; 1939-6376
• DOI: 10.3109/19396368.2011.603792

We retrospectively analyzed 6,360 artificial insemination cycles of husband's semen through intrauterine insemination (AIH-IUI) or artificial insemination with donor semen through intrauterine insemination (AID-IUI) in patients with infertility between August, 1998 and August, 2010. The relationship between processed total motile sperm count (PTMS) and pregnancy outcome was determined. The study was divided into 6 groups according to PTMS. Group 1: ≤ 2.0 million, Group 2: 2.1-4.0 million, Group 3: 4.1-6.0 million, Group 4: 6.1-8.0 million, Group 5: 8.1-10.0 million, and Group 6: >10.0 million. There was no statistically significant difference in age, duration of infertility, unilateral tubal patency, induced ovulation, and single IUI or double IUI between the 6 groups in both AIH-IUI and AID-IUI. The total clinical pregnancy rate of AIH-IUI was 10.81 % and AID-IUI was 27.52 %. Among the 6 groups, the clinical pregnancy rate was the lowest in Group 1 (P