Polypyrrole Nanoparticles: A Potential Optical Coherence Tomography Contrast Agent for Cancer Imaging

A near‐infrared (NIR) absorbing contrast agent based on polypyrrole nanoparticles is described. Quantitative optical coherence tomography studies on tissue phantoms and Mie scattering calculations indicate their potential application for early‐stage cancer diagnosis.

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2011-12, Vol.23 (48), p.5792-5795
Main Authors: Au, Kin Man, Lu, Zenghai, Matcher, Stephen J., Armes, Steven P.
Format: Article
Language:English
Subjects:
cancer imaging
contrast agents
Contrast Media - pharmacology
Diagnostic Imaging - methods
Humans
Medical Oncology - methods
Models, Statistical
Nanoparticles - chemistry
Neoplasms - diagnosis
optical coherence tomography
Phantoms, Imaging
Polymers - chemistry
polypyrrole
Pyrroles - chemistry
Scattering, Radiation
Spectrophotometry, Ultraviolet - methods
Spectroscopy, Near-Infrared - methods
Tomography, Optical Coherence - methods
Online Access:Get full text
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Description
Summary:A near‐infrared (NIR) absorbing contrast agent based on polypyrrole nanoparticles is described. Quantitative optical coherence tomography studies on tissue phantoms and Mie scattering calculations indicate their potential application for early‐stage cancer diagnosis.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201103190