A role for C-terminal cross-linking telopeptide (CTX) level to predict the development of bisphosphonate-related osteonecrosis of the jaws (BRONJ) following oral surgery?

Background Bisphosphonates are a class of chemical compounds used in the treatment of a variety of bone-related conditions. Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a well-recognised complication. C-terminal cross-linking telopeptide (CTX) estimation has been suggested as an indic...

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Bibliographic Details
Published in:Irish journal of medical science 2012-06, Vol.181 (2), p.237-242
Main Authors: O’Connell, J. E., Ikeagwani, O., Kearns, G. J.
Format: Article
Language:English
Subjects:
Adult
Aged
Bisphosphonate-Associated Osteonecrosis of the Jaw - blood
Bisphosphonate-Associated Osteonecrosis of the Jaw - etiology
Bone Density Conservation Agents - adverse effects
Collagen Type I - blood
Diphosphonates - adverse effects
Family Medicine
Female
General Practice
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Peptides - blood
Predictive Value of Tests
Tooth Extraction - adverse effects
Online Access:Get full text
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Summary:Background Bisphosphonates are a class of chemical compounds used in the treatment of a variety of bone-related conditions. Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a well-recognised complication. C-terminal cross-linking telopeptide (CTX) estimation has been suggested as an indicator for the risk of BRONJ. It was reported that values
ISSN:0021-1265
1863-4362
DOI:10.1007/s11845-011-0790-5