Chemical composition and antibacterial activity of the volatile oil from seeds of Artemisia annua L. from Iran

The composition of essential oil of the seeds of Artemisia annua L. was analysed by GC-MS. Overall, 16 volatile components were identified on the basis of their mass spectra characteristics and retention indices representing 95.5% of the total oil. Trans-3(10)-caren-4-ol (22.3%), artemisia ketone (1...

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Bibliographic Details
Published in:Natural product research 2013-01, Vol.27 (2), p.198-200
Main Authors: Habibi, Zohreh, Ghanian, Shamimeh, Ghasemi, Sabrieh, Yousefi, Maryam
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Artemisia annua
Artemisia annua - chemistry
Enterococcus faecalis - drug effects
Escherichia coli - drug effects
essential oil
Gas Chromatography-Mass Spectrometry
Iran
Microbial Sensitivity Tests
Oils, Volatile - analysis
Oils, Volatile - isolation & purification
Oils, Volatile - pharmacology
Plant Extracts - analysis
Plant Extracts - isolation & purification
Plant Extracts - pharmacology
seed
Seeds - chemistry
Terpenes - analysis
Terpenes - isolation & purification
Terpenes - pharmacology
trans- 3-caren-4-ol, artemisia ketone
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Summary:The composition of essential oil of the seeds of Artemisia annua L. was analysed by GC-MS. Overall, 16 volatile components were identified on the basis of their mass spectra characteristics and retention indices representing 95.5% of the total oil. Trans-3(10)-caren-4-ol (22.3%), artemisia ketone (18.6%), 1,8-cineole (14.9%), δ-selinene (13.0%) and α-pinene (8.2%) were the major compounds. Oxygenated monoterpenes were the main compounds with 51.6% followed by sesquiterpene hydrocarbons (13.3%), monoterpene hydrocarbons (9.9%) and other compounds (8.3%). The essential oil was highly active against Escherichia coli and Enterococcus faecalis.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2012.662652