Hypercalcitoninemia, Hypocalcemia, and Toxic Shock Syndrome

Toxic shock syndrome is a multisystem illness frequently complicated by hypocalcemia. The etiology of the hypocalcemia, which may be severe, is not well understood. We report two cases of fatal toxic shock syndrome accompanied by severe hypocalcemia; each patient also had an inappropriately elevated...

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Bibliographic Details
Published in:Reviews of infectious diseases 1990-09, Vol.12 (5), p.736-739
Main Authors: SPERBER, S. J, BLEVINS, D. D, FRANCIS, J. B
Format: Article
Language:English
Subjects:
Adolescent
Adult
Bacterial diseases
Biological and medical sciences
Blood
Calcitonin - blood
Calcium
Clinical Infectious Disease Articles
Diarrhea
Disease outbreaks
Diseases
Female
Hormones
Humans
Hypocalcemia
Hypocalcemia - etiology
Infectious diseases
Lung diseases
Magnesium
Male
Medical sciences
Shock, Septic - complications
Toxicity
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Summary:Toxic shock syndrome is a multisystem illness frequently complicated by hypocalcemia. The etiology of the hypocalcemia, which may be severe, is not well understood. We report two cases of fatal toxic shock syndrome accompanied by severe hypocalcemia; each patient also had an inappropriately elevated serum calcitonin level, which in one case was as high as 179,000 pg/mL. Hypercalcitoninemia may be a cause of the low serum calcium levels as well as of certain clinical manifestations of toxic shock syndrome.
ISSN:0162-0886