Prevalence of recurrence and retreatment of ruptured intracranial aneurysms treated with endovascular coil occlusion

• Published in: British journal of neurosurgery 2013-02, Vol.27 (1), p.30-33
• Main Authors: Corns, Robert, Zebian, Bassel, Tait, Matthew J., Walsh, Daniel, Hampton, Timothy, Deasy, Neil, Tolias, Christos
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; aneurysm; Aneurysm, Ruptured - diagnostic imaging; Aneurysm, Ruptured - therapy; Aneurysms; Cerebral Angiography; Embolization, Therapeutic - methods; Embolization, Therapeutic - statistics & numerical data; endovascular treatment; Head injuries; Health risk assessment; Humans; Intracranial Aneurysm - diagnostic imaging; Intracranial Aneurysm - therapy; Middle Aged; Neurology; Neurosurgery; Recurrence; retreatment; Retreatment - statistics & numerical data; Retrospective Studies; subarachnoid haemorrhage; Subarachnoid Hemorrhage - diagnostic imaging; Subarachnoid Hemorrhage - etiology; Subarachnoid Hemorrhage - therapy; Survival analysis; Young Adult
• ISSN: 0268-8697; 1360-046X
• DOI: 10.3109/02688697.2012.701676

Abstract Object. Endovascular coiling is a common treatment for ruptured intracranial aneurysms. However, concerns have been raised over the durability of this treatment. The aim of this study was to establish the rate of recurrence and retreatment of coiled aneurysms treated in our unit. Methods. We performed a retrospective analysis of 264 surviving patients with ruptured aneurysms treated by endovascular coiling between November 2003 and April 2007. Data was collected on patient age, location of aneurysm, angiogram results and any subsequent retreatment. Results. Follow-up angiography performed at 6 months was available in 239 cases (91%) and revealed 158 (66%) aneurysms completely occluded, 51 (21%) had neck recurrence and 31 (13%) had significant recurrence. Thirty (12.6%) aneurysms required retreatment over a mean follow-up period of 46 (range 24-66) months. Younger age predisposed to a higher risk of recurrence and retreatment. Aneurysms of the anterior communicating and anterior cerebral arteries were less likely to recur or require retreatment (relative risk 0.42 and 0.29, respectively); aneurysms of the posterior communicating arteries were more likely to recur (relative risk 2.22). Aneurysms of the basilar and carotid arteries were more likely to undergo retreatment (relative risk 2.84 and 2.46, respectively). Conclusion. Long-term follow-up is required for ruptured aneurysms treated by coiling. Certain subgroups may require closer follow-up due to the increased risk of recurrence or retreatment, such as younger patients and those with aneurysms of the posterior communicating, basilar or carotid arteries.