Severe chronic blepharitis and scarring ectropion associated with discoid lupus erythematosus

Discoid lupus erythematosus is a common form of chronic cutaneous lupus erythematosus, an autoimmune inflammatory disease that affects most of the human organs, including the skin, kidneys, joints, heart and lungs. We describe a 45-year-old Caucasian woman with a 21-year history of eyelid redness an...

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Bibliographic Details
Published in:Clinical and experimental optometry 2013-01, Vol.96 (1), p.124-125
Main Authors: Kopsachilis, Nikolaos, Tsaousis, Konstantinos T, Tourtas, Theofilos, Tsinopoulos, Ioannis T
Format: Article
Language:English
Subjects:
Biopsy
Blepharitis - diagnosis
Blepharitis - etiology
chronic blepharitis
Chronic Disease
Cicatrix - complications
Cicatrix - pathology
Diagnosis, Differential
ectropion
Ectropion - diagnosis
Ectropion - etiology
Eyelids - pathology
Female
Humans
lupus erythematosus
Lupus Erythematosus, Discoid - complications
Lupus Erythematosus, Discoid - diagnosis
madarosis
Middle Aged
Severity of Illness Index
Skin - pathology
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Summary:Discoid lupus erythematosus is a common form of chronic cutaneous lupus erythematosus, an autoimmune inflammatory disease that affects most of the human organs, including the skin, kidneys, joints, heart and lungs. We describe a 45-year-old Caucasian woman with a 21-year history of eyelid redness and irritation. She had been treated with antibiotics, steroids and eyelid hygiene, a therapy that resulted to brief periods of relief of symptoms. In the last 12 months, her symptoms seemed to have exacerbated, despite the administration of a local therapy. Following biopsy, a diagnosis of discoid lupus erythematosus was confirmed and the patient was placed on a systemic therapy with hydroxychloroquine. The eyelid inflammation decreased but severe scarring of the marginal eyelids persisted, resulting in cicatricial ectropion.
ISSN:0816-4622
1444-0938
DOI:10.1111/j.1444-0938.2012.00777.x